Progress and Challenges in Microalgal Large-Scale Production

Contact: Belén Benito García
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Microalgae have been proposed as an alternative to conventional processes for the supply of foods and feeds, biomaterials and biofuels, and including for wastewater treatment and capture of CO2 from flue gases. In this sense, the worldwide production of microalgae is growing very fast although still, the overall production capacity is quite limited, in the range of 50 kt per year. To enlarge the contribution of microalgae to the bioeconomy large efforts must be devoted to the enlargement of current production facilities, especially by better understanding the biological phenomena taking place on these systems.

Thus, microalgae are photosynthetic organisms capable of using sunlight as an energy source to produce valuable biomass, and at the same time release the oxygen produced into the environment (Figure 1). These organisms are characterized by having a simple nutritional demand, they can grow in water ponds with nitrogen, phosphorus, light and atmospheric CO2 as a carbon source. Unlike plants, which also photosynthesize, microalgae are more efficient at converting solar energy, grow faster, and can be produced on non-arable land. These characteristics have made microalgae a valuable and sustainable source of biomass.



Figure 1. Microalgae observed with the optical microscope


The technology to produce microalgae has been in use for decades. Currently, specific equipment, called photobioreactors, are used for its production on an industrial scale. Although there are different types of photobioreactors, raceway reactors are the most widely used (Figure 2). These systems are open channels with a depth of 15-30 centimetres, through which the microalgae culture is in continuous movement due to the action of paddle wheels. In microalgae culture systems, the decisive parameters for their growth such as temperature, pH or dissolved oxygen are continuously monitored. Although control strategies have been developed to optimize these systems and technology has been improved over the years, they still have several drawbacks. The main challenge in the production of microalgae is to achieve stable cultures that are maintained over long periods despite the environmental or operational disturbances that occur daily.



Figure 2. Raceway reactors utilized during the PRODIGIO project.


During the development of the PRODIGIO project, in-depth monitoring of the microalgae cultures is being carried out to understand what causes the collapse of the cultures and the failure of these biological systems. Quite a challenge that is already beginning to give its first results.


Article written by Ana Sánchez Zurano, researcher at Almería University.

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About Prodigio Project

PRODIGIO is an EU-funded project that plan to establish a base of knowledge for the development of system failure prediction technologies that increase the performance of microalgae production and anaerobic digestion systems and advance towards more favourable techno-economic, environmental and social performance to achieve more sustainable microalgae biogas. The project aims to decode the triggers, identify early-warnings, define threshold values, and calculate warning times for critical state transitions in bioreactors. The technology behind the project could contribute to increasing resource and energy efficiencies >50% throughout the production chain, which would translate into OPEX savings and GHG emissions reduction. The results of the project will pave the way for moving the entire microalgae biogas production chain efficiently towards its theoretical maximum, enabling the development of a fully integrated and truly sustainable microalgae biogas production industry and contributing to strengthening the EU's leadership in renewable fuel technologies. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101007006. Visit for more information.

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About IDConsortium

IDConsortium is a consultancy firm founded in Seville, Spain, in 2009 with the aim of helping researchers and businesses to internationalise and showcase their R&D by joining international consortiums to pursue different lines of research, development, and innovation. The firm is an offshoot of IDAction S.L., a company with a wide range of experience in managing R&D, innovation, and investment projects. We help promote clusters and sectorial organizations reach their potential at a national and international level. With our experience and involvement in various international innovation projects, we provide strategic advice in the following areas: Industrial Biotechnology, Advanced production systems in Agriculture, Livestock and Aquaculture based on Industry 4.0., and Innovative systems while promoting an active, healthy, and sustainable aging. Visit for more information.